Cell biology is the science of life at its smallest scale. Our free PDF cell biology books cover how cells are built, how they divide, how they communicate, and how they go wrong in disease.
Every book on this page is open access and free to download, with no registration. They are grouped into complete textbooks, guides on cell structure and function, stem cell biology, and cancer cell biology.
Pick the textbook that fits your level and download it in one click. Whether you study cell signaling, mitosis, or the genetics of cancer, you will find a book here that explains it without paywalls.
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Textbooks
Cell Biology Textbooks
These textbooks introduce the full landscape of the field: cell theory, the plasma membrane, organelles, energy metabolism, DNA replication, transcription, signal transduction, and the cell cycle. They are written for undergraduate and pre-clinical students.
Open Oregon textbook covering microscopy, biological membranes, DNA and chromosomes, the nucleus, endomembrane system, vesicle transport, and the Golgi apparatus.
Pre-clinical reference integrating cell biology, genetics, and biochemistry. Covers DNA replication, transcription, translation, metabolism, cell signaling, and the extracellular matrix.
College-level cell and molecular biology textbook focused on membrane transport, energy production, gene expression, the cytoskeleton, and immune cell mechanisms.
Comprehensive cell and molecular biology textbook that explains current knowledge alongside the experiments that established it. Spans membranes, organelles, gene expression, the cytoskeleton, and signaling.
Concept-based notes for biotechnology students covering cell structural organization, membrane transport, receptors, signal transduction, and cell culture in a question-and-answer format.
University course material covering cell structure, membrane biology, organelle function, the cell cycle, and the molecular biology of DNA replication, transcription, and the genetic code.
Introductory cell biology textbook covering the scientific method, properties of life, prokaryotic vs eukaryotic cells, the plasma membrane, organelles, the cytoskeleton, and the cell cycle.
These shorter resources zoom into the architecture of the cell: the membrane, the cytoskeleton, the nucleus, and each major organelle. They are useful as a first read or as a refresher before tackling a full textbook.
Richly illustrated NIH booklet introducing the basics of cell biology, organelles, the cytoskeleton, cell division, signaling, and how cells handle stress and disease.
The National Institute of General Medical Sciences (NIGMS)
CK-12 introduction to cell biology covering the history of cell discovery, the cell theory, prokaryotic and eukaryotic cells, and the four common parts of all cells.
Stem cell biology focuses on cells that can self-renew and differentiate into specialized cell types. These books cover embryonic, somatic, and induced pluripotent stem cells, with their applications in tissue engineering and regenerative medicine.
National Academies booklet explaining what stem cells are, the different types, how researchers work with them, why stem cell research matters, and the ethical context around the field.
Classroom curriculum on stem cell biology with hands-on activities, models, and case studies. Introduces stem cell basics, pluripotent stem cell lines, gene expression in stem cell differentiation, and therapeutic applications.
University of Rochester Life Sciences Learning Center
Cancer biology studies how a normal cell becomes a tumor cell through mutation, loss of cell cycle control, and dysregulated signaling. These free textbooks introduce oncogenes, tumor suppressors, and the hallmarks of cancer.
A concise cancer biology textbook for students with or without a biology background. Covers how cancer arises, the six hallmarks of cancer, oncogenes, tumor suppressor genes, sustained growth signals, and cancer epigenetics.
Six learning experiences that teach the cell cycle in the context of cancer. Explores mitosis, gene mutations, uncontrolled cell division, and the feedback mechanisms that normally keep cell proliferation in check.
University of Rochester Life Sciences Learning Center